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Dokumenttyp:
journal article 
Autor(en):
Schuster, IG; Busch, DH; Eppinger, E; Kremmer, E; Milosevic, S; Hennard, C; Kuttler, C; Ellwart, JW; Frankenberger, B; Nössner, E; Salat, C; Bogner, C; Borkhardt, A; Kolb, HJ; Krackhardt, AM 
Titel:
Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies. 
Abstract:
Cell-based immunotherapy in settings of allogeneic stem cell transplantation or donor leukocyte infusion has curative potential, especially in hematologic malignancies. However, this approach is severely restricted due to graft-versus-host disease (GvHD). This limitation may be overcome if target antigens are molecularly defined and effector cells are specifically selected. We chose formin-related protein in leukocytes 1 (FMNL1) as a target antigen after intensive investigation of its expression...    »
 
Zeitschriftentitel:
Blood 
Jahr:
2007 
Band / Volume:
110 
Heft / Issue:
Seitenangaben Beitrag:
2931-9 
Sprache:
eng 
Print-ISSN:
0006-4971 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene; III. Medizinische Klinik und Poliklinik