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Document type:
journal article 
Author(s):
Sternfeld, T; Schmid, M; Tischleder, A; Mudra, S; Schlamp, A; Kost, BP; Gruber, R; Youle, M; Bogner, JR; Goebel, FD 
Title:
The influence of HIV infection and antiretroviral therapy on the mitochondrial membrane potential of peripheral mononuclear cells. 
Abstract:
OBJECTIVES: Clinical disorders occurring in HIV-infected patients on antiretroviral therapy (ART) have been linked to mitochondrial dysfunction, for example, lactic acidosis and lipodystrophy. Mitochondrial membrane potential (delta psi m) is the most direct measure of the state of energization of the mitochondria. We analysed delta psi m, of peripheral blood mononuclear cells (PBMCs) in HIV-negative, healthy subjects (n=8), HIV-infected, treatment-naive patients (n=30), and HIV-infected patient...    »
 
Journal title abbreviation:
Antivir Ther 
Year:
2007 
Journal volume:
12 
Journal issue:
Pages contribution:
769-78 
Language:
eng 
Print-ISSN:
1359-6535 
TUM Institution:
II. Medizinische Klinik und Poliklinik