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Document type:
journal article 
Author(s):
Yüce, B; Sibaev, A; Haaken, A; Saur, D; Allescher, HD; Göke, B; Timmermans, JP; Storr, M 
Title:
ORL-1 receptor mediates the action of nociceptin on ascending myenteric reflex pathways in rats. 
Abstract:
BACKGROUND AND AIMS: Nociceptin is the endogenous agonist of the "orphan" opioid receptor-1 (ORL-1). We investigated whether activation of the ORL-1 receptor influences smooth muscle contractility and enteric neurotransmission within ascending myenteric reflex pathways of rats. METHODS: Reverse transcriptase polymerase chain reaction was performed to evaluate the presence of ORL-1 receptors. The ascending part of the ascending myenteric reflex in rats was studied in ileal segments using a 3-cham...    »
 
Journal title abbreviation:
Gastroenterology 
Year:
2007 
Journal volume:
133 
Journal issue:
Pages contribution:
574-86 
Language:
eng 
Print-ISSN:
0016-5085 
TUM Institution:
II. Medizinische Klinik und Poliklinik