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Dokumenttyp:
journal article 
Autor(en):
Rebholz, B; Haase, I; Eckelt, B; Paxian, S; Flaig, MJ; Ghoreschi, K; Nedospasov, SA; Mailhammer, R; Debey-Pascher, S; Schultze, JL; Weindl, G; Förster, I; Huss, R; Stratis, A; Ruzicka, T; Röcken, M; Pfeffer, K; Schmid, RM; Rupec, RA 
Titel:
Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin. 
Abstract:
Inflammatory diseases at epithelial borders develop from aberrant interactions between resident cells of the tissue and invading immunocytes. Here, we unraveled basic functions of epithelial cells and immune cells and the sequence of their interactions in an inflammatory skin disease. Ubiquitous deficiency of the IkappaBalpha protein (Ikba(Delta)(/Delta)) as well as concomitant deletion of Ikba specifically in keratinocytes and T cells (Ikba(K5Delta/K5Delta lckDelta/lckDelta)) resulted in an inf...    »
 
Zeitschriftentitel:
Immunity 
Jahr:
2007 
Band / Volume:
27 
Heft / Issue:
Seitenangaben Beitrag:
296-307 
Sprache:
eng 
Print-ISSN:
1074-7613 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik