User: Guest  Login
Document type:
journal article 
Author(s):
Burgermeister, E; Xing, X; Röcken, C; Juhasz, M; Chen, J; Hiber, M; Mair, K; Shatz, M; Liscovitch, M; Schmid, RM; Ebert, MP 
Title:
Differential expression and function of caveolin-1 in human gastric cancer progression. 
Abstract:
Caveolin-1 is a scaffold protein of caveolae that acts as a tumor modulator by interacting with cell adhesion molecules and signaling receptors. The role of caveolin-1 in the pathogenesis of gastric cancer (GC) is currently unknown. We show by confocal immunofluorescence microscopy and immunohistochemistry of biopsies from GC patients (n = 41) that the nonneoplastic mucosa expressed caveolin-1 in foveolar epithelial cells and adjacent connective tissue. GC cells of only 3 of 41 (7%) patients exp...    »
 
Journal title abbreviation:
Cancer Res 
Year:
2007 
Journal volume:
67 
Journal issue:
18 
Pages contribution:
8519-26 
Language:
eng 
Print-ISSN:
0008-5472 
TUM Institution:
II. Medizinische Klinik und Poliklinik