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Dokumenttyp:
journal article 
Autor(en):
Massberg, S; Schaerli, P; Knezevic-Maramica, I; Köllnberger, M; Tubo, N; Moseman, EA; Huff, IV; Junt, T; Wagers, AJ; Mazo, IB; von Andrian, UH 
Titel:
Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. 
Abstract:
Constitutive egress of bone marrow (BM)-resident hematopoietic stem and progenitor cells (HSPCs) into the blood is a well-established phenomenon, but the ultimate fate and functional relevance of circulating HSPCs is largely unknown. We show that mouse thoracic duct (TD) lymph contains HSPCs that possess short- and long-term multilineage reconstitution capacity. TD-derived HSPCs originate in the BM, enter the blood, and traffic to multiple peripheral organs, where they reside for at least 36 hr...    »
 
Zeitschriftentitel:
Cell 
Jahr:
2007 
Band / Volume:
131 
Heft / Issue:
Seitenangaben Beitrag:
994-1008 
Sprache:
eng 
Print-ISSN:
0092-8674 
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik