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Document type:
journal article 
Author(s):
Müller, TD; Reichwald, K; Wermter, AK; Brönner, G; Nguyen, TT; Friedel, S; Koberwitz, K; Engeli, S; Lichtner, P; Meitinger, T; Schäfer, H; Hebebrand, J; Hinney, A 
Title:
No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescents. 
Abstract:
Studies in rodent models demonstrated that the central cannabinoid receptor (Cnr1) mediates the orexigenic effects of cannabinoids. To analyze whether genetic variation in the cannabinoid receptor gene (CNR1) is implicated in human obesity, we initially genotyped 8 single nucleotide polymorphisms (SNPs) located in the 5' region (rs9353527, rs754387, rs6454676), intron 2 (rs806379, rs1535255), exon 3 (rs2023239), intron 3 (rs806370) and the coding region (rs1049353) in up to 364 German obesity tr...    »
 
Journal title abbreviation:
Mol Genet Metab 
Year:
2007 
Journal volume:
90 
Journal issue:
Pages contribution:
429-34 
Language:
eng 
Print-ISSN:
1096-7192 
TUM Institution:
Institut für Humangenetik