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Dokumenttyp:
journal article 
Autor(en):
Winkelmann, J; Schormair, B; Lichtner, P; Ripke, S; Xiong, L; Jalilzadeh, S; Fulda, S; Pütz, B; Eckstein, G; Hauk, S; Trenkwalder, C; Zimprich, A; Stiasny-Kolster, K; Oertel, W; Bachmann, CG; Paulus, W; Peglau, I; Eisensehr, I; Montplaisir, J; Turecki, G; Rouleau, G; Gieger, C; Illig, T; Wichmann, HE; Holsboer, F; Müller-Myhsok, B; Meitinger, T 
Titel:
Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. 
Abstract:
Restless legs syndrome (RLS) is a frequent neurological disorder characterized by an imperative urge to move the legs during night, unpleasant sensation in the lower limbs, disturbed sleep and increased cardiovascular morbidity. In a genome-wide association study we found highly significant associations between RLS and intronic variants in the homeobox gene MEIS1, the BTBD9 gene encoding a BTB(POZ) domain as well as variants in a third locus containing the genes encoding mitogen-activated protei...    »
 
Zeitschriftentitel:
Nat Genet 
Jahr:
2007 
Band / Volume:
39 
Heft / Issue:
Seitenangaben Beitrag:
1000-6 
Sprache:
eng 
Print-ISSN:
1061-4036 
TUM Einrichtung:
r Humangenetik