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Dokumenttyp:
journal article 
Autor(en):
Steinbach, S; Lutz, J 
Titel:
Glutamate induces apoptosis in cultured spiral ganglion explants. 
Abstract:
Traumatic sound exposure, aminoglycoside antibiotics, cochlea ischemia or traumatic stress leads to an excessive release of glutamate from inner hair cells into the synaptic cleft. The high glutamate concentration can cause a swelling and destruction of the dendrites of spiral ganglion neurons of type I as well as a reduction in the number of neurons. This may be a cause of hearing loss. The mechanism causing the reduction of neurons is still not known. Apoptosis, also called programmed cell dea...    »
 
Zeitschriftentitel:
Biochem Biophys Res Commun 
Jahr:
2007 
Band / Volume:
357 
Heft / Issue:
Seitenangaben Beitrag:
14-9 
Sprache:
eng 
Print-ISSN:
0006-291X 
TUM Einrichtung:
Hals-, Nasen-, Ohrenklinik und Poliklinik; r Nephrologie