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Dokumenttyp:
journal article 
Autor(en):
Penz, SM; Reininger, AJ; Toth, O; Deckmyn, H; Brandl, R; Siess, W 
Titel:
Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques. 
Abstract:
Anti-platelet drugs are used to prevent intra-arterial thrombus formation after rupture of atherosclerotic plaques. Until now, the inhibitory effect of present and future anti-platelet drugs such as aspirin, ADP receptor P2Y(1)/P2Y(12) antagonists and glycoprotein (GP) Ibalpha inhibitors on the interaction of platelets with human plaques is not known. To study those effects we obtained human atherosclerotic plaques by surgical endarterectomy. Plaques induced maximal platelet aggregation in hirud...    »
 
Zeitschriftentitel:
Thromb Haemost 
Jahr:
2007 
Band / Volume:
97 
Heft / Issue:
Seitenangaben Beitrag:
435-43 
Sprache:
eng 
Print-ISSN:
0340-6245 
TUM Einrichtung:
chirurgie