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Document type:
journal article 
Author(s):
Golda, A; Pelisek, J; Klocke, R; Engelmann, MG; Rolland, PH; Mekkaoui, C; Nikol, S 
Title:
Small poly-L-lysines improve cationic lipid-mediated gene transfer in vascular cells in vitro and in vivo. 
Abstract:
The potential of two small poly-L-lysines (sPLLs), low molecular weight sPLL (LMW-L) containing 7-30 lysine residues and L18 with 18 lysine repeats, to enhance the efficiency of liposome-mediated gene transfer (GT) with cationic lipid DOCSPER [1,3-dioleoyloxy-2-(N(5)-carbamoyl-spermine)-propane] in vascular smooth muscle cells (SMCs) was investigated. Dynamic light scattering was used for determination of particle size. Confocal microscopy was applied for colocalization studies of sPLLs and plas...    »
 
Journal title abbreviation:
J Vasc Res 
Year:
2007 
Journal volume:
44 
Journal issue:
Pages contribution:
273-82 
Language:
eng 
Print-ISSN:
1018-1172 
TUM Institution:
chirurgie