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Dokumenttyp:
journal article 
Autor(en):
Golda, A; Pelisek, J; Klocke, R; Engelmann, MG; Rolland, PH; Mekkaoui, C; Nikol, S 
Titel:
Small poly-L-lysines improve cationic lipid-mediated gene transfer in vascular cells in vitro and in vivo. 
Abstract:
The potential of two small poly-L-lysines (sPLLs), low molecular weight sPLL (LMW-L) containing 7-30 lysine residues and L18 with 18 lysine repeats, to enhance the efficiency of liposome-mediated gene transfer (GT) with cationic lipid DOCSPER [1,3-dioleoyloxy-2-(N(5)-carbamoyl-spermine)-propane] in vascular smooth muscle cells (SMCs) was investigated. Dynamic light scattering was used for determination of particle size. Confocal microscopy was applied for colocalization studies of sPLLs and plas...    »
 
Zeitschriftentitel:
J Vasc Res 
Jahr:
2007 
Band / Volume:
44 
Heft / Issue:
Seitenangaben Beitrag:
273-82 
Sprache:
eng 
Print-ISSN:
1018-1172 
TUM Einrichtung:
chirurgie