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Document type:
journal article 
Author(s):
Holzapfel, C; Klopp, N; Grallert, H; Huth, C; Gieger, C; Meisinger, C; Strassburger, K; Giani, G; Wichmann, HE; Laumen, H; Hauner, H; Herder, C; Rathmann, W; Illig, T 
Title:
Genetic variants in the leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12) gene are not associated with T2DM and related parameters in Caucasians (KORA study). 
Abstract:
OBJECTIVE: The aim of our study was to determine the variant pattern of the leukemia-associated Rho guanine nucleotide exchange factor (LARG, or ARHGEF12) gene and investigate whether LARG variants are associated with diabetes mellitus type 2 (T2DM), the metabolic syndrome (MetS), or related parameters such as insulin sensitivity in German Caucasians. DESIGN: We analyzed single nucleotide polymorphisms (SNPs) in the LARG gene in the 55-74-year-old individuals of the population-based German Cauca...    »
 
Journal title abbreviation:
Eur J Endocrinol 
Year:
2007 
Journal volume:
157 
Journal issue:
Pages contribution:
R1-5 
Language:
eng 
Print-ISSN:
0804-4643 
TUM Institution:
hrungsmedizin