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Document type:
journal article 
Author(s):
Mariani, V; Gilles, S; Jakob, T; Thiel, M; Mueller, MJ; Ring, J; Behrendt, H; Traidl-Hoffmann, C 
Title:
Immunomodulatory mediators from pollen enhance the migratory capacity of dendritic cells and license them for Th2 attraction. 
Abstract:
The immune response of atopic individuals against allergens is characterized by increased levels of Th2 cytokines and chemokines. However, the way in which the cytokine/chemokine profile is matched to the type of invading allergen, and why these profiles sometimes derail and lead to disease, is not well understood. We recently demonstrated that pollen modulates dendritic cell (DC) function in a way that results in an enhanced capacity to initiate Th2 responses in vitro. Here, we examined the eff...    »
 
Journal title abbreviation:
J Immunol 
Year:
2007 
Journal volume:
178 
Journal issue:
12 
Pages contribution:
7623-31 
Language:
eng 
Print-ISSN:
0022-1767 
TUM Institution:
r Dermatologie und Allergologie