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Document type:
journal article 
Author(s):
Papadopoulos, NG; Xepapadaki, P; Mallia, P; Brusselle, G; Watelet, JB; Xatzipsalti, M; Foteinos, G; van Drunen, CM; Fokkens, WJ; D'Ambrosio, C; Bonini, S; Bossios, A; Lötvall, J; van Cauwenberge, P; Holgate, ST; Canonica, GW; Szczeklik, A; Rohde, G; Kimpen, J; Pitkäranta, A; Mäkelä, M; Chanez, P; Ring, J; Johnston, SL 
Title:
Mechanisms of virus-induced asthma exacerbations: state-of-the-art. A GA2LEN and InterAirways document. 
Abstract:
Viral infections of the respiratory tract are the most common precipitants of acute asthma exacerbations. Exacerbations are only poorly responsive to current asthma therapies and new approaches to therapy are needed. Viruses, most frequently human rhinoviruses (RV), infect the airway epithelium, generate local and systemic immune responses, as well as neural responses, inducing inflammation and airway hyperresponsiveness. Using in vitro and in vivo experimental models the role of various proinfl...    »
 
Journal title abbreviation:
Allergy 
Year:
2007 
Journal volume:
62 
Journal issue:
Pages contribution:
457-70 
Language:
eng 
Print-ISSN:
0105-4538 
TUM Institution:
r Dermatologie und Allergologie