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Document type:
journal article 
Author(s):
Abal, M; Fsihi, H; Bras-Gonçalves, R; Doll, A; Boyé, K; Janssen, KP; Alameda, F; Reventós, J; Louvard, D; Magdelenat, H; Poupon, MF; Robine, S 
Title:
Heterogeneous metastasis efficiency of isogenic orthotopic colon cancer xenografts reveals distinctive gene expression profiles. 
Abstract:
Hepatic and lung metastases are the leading causes of mortality and major indicators of aggressiveness in colorectal cancer. The underlying molecular mechanisms contributing to the development of metastasis are still unclear. Here, we designed a novel approach to explore gene expression profiles associated with metastasis in human colorectal cancer (hCRC). A series of ten isogenic tumors from three different hCRC models were orthotopically implanted into nude mice. In these series, we analyzed t...    »
 
Journal title abbreviation:
Tumour Biol 
Year:
2007 
Journal volume:
28 
Journal issue:
Pages contribution:
139-50 
Language:
eng 
Print-ISSN:
1010-4283 
TUM Institution:
Chirurgiesche Klinik und Poliklinik