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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Singh, AP; Shah, PP; Mathur, N; Buters, JT; Pant, MC; Parmar, D 
Title:
Genetic polymorphisms in cytochrome P4501B1 and susceptibility to head and neck cancer. 
Abstract:
Cytochrome P4501B1 (CYP1B1), a polycyclic aromatic hydrocarbon (PAH) metabolizing CYP, is genetically polymorphic in humans and may be involved in the individual susceptibility to chemical-induced cancer. In the present study, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) in CYP1B1 that cause amino acid changes (Arg-Gly at codon 48, Ala-Ser at codon 119, Leu-Val at codon 432 and Asn-Ser at codon 453) were studied in 150 cases suffering from head and neck squam...    »
 
Journal title abbreviation:
Mutat Res 
Year:
2008 
Journal volume:
639 
Journal issue:
1-2 
Pages contribution:
11-9 
Language:
eng 
Print-ISSN:
0027-5107 
TUM Institution:
Molekulare Allergologie (Prof. Schmidt-Weber)