Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Singh, AP; Shah, PP; Mathur, N; Buters, JT; Pant, MC; Parmar, D 
Titel:
Genetic polymorphisms in cytochrome P4501B1 and susceptibility to head and neck cancer. 
Abstract:
Cytochrome P4501B1 (CYP1B1), a polycyclic aromatic hydrocarbon (PAH) metabolizing CYP, is genetically polymorphic in humans and may be involved in the individual susceptibility to chemical-induced cancer. In the present study, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) in CYP1B1 that cause amino acid changes (Arg-Gly at codon 48, Ala-Ser at codon 119, Leu-Val at codon 432 and Asn-Ser at codon 453) were studied in 150 cases suffering from head and neck squam...    »
 
Zeitschriftentitel:
Mutat Res 
Jahr:
2008 
Band / Volume:
639 
Heft / Issue:
1-2 
Seitenangaben Beitrag:
11-9 
Sprache:
eng 
Print-ISSN:
0027-5107 
TUM Einrichtung:
r Molekulare Allergologie und Umweltforschung