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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Burgler, S; Mantel, PY; Bassin, C; Ouaked, N; Akdis, CA; Schmidt-Weber, CB 
Title:
RORC2 is involved in T cell polarization through interaction with the FOXP3 promoter. 
Abstract:
The process of Th cell differentiation toward polarized effector T cells tailors specific immunity against invading pathogens while allowing tolerance against commensal microorganisms, harmless allergens, or autologous Ags. Identification of the mechanisms underlying this polarization process is therefore central to understand how the immune system confers immunity and tolerance. The present study demonstrates that retinoic acid receptor-related orphan receptor C2 (RORC2), a key transcription fa...    »
 
Journal title abbreviation:
J Immunol 
Year:
2010 
Journal volume:
184 
Journal issue:
11 
Pages contribution:
6161-9 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0022-1767 
TUM Institution:
Molekulare Allergologie (Prof. Schmidt-Weber)