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Dokumenttyp:
journal article 
Autor(en):
Burgler, S; Mantel, PY; Bassin, C; Ouaked, N; Akdis, CA; Schmidt-Weber, CB 
Titel:
RORC2 is involved in T cell polarization through interaction with the FOXP3 promoter. 
Abstract:
The process of Th cell differentiation toward polarized effector T cells tailors specific immunity against invading pathogens while allowing tolerance against commensal microorganisms, harmless allergens, or autologous Ags. Identification of the mechanisms underlying this polarization process is therefore central to understand how the immune system confers immunity and tolerance. The present study demonstrates that retinoic acid receptor-related orphan receptor C2 (RORC2), a key transcription fa...    »
 
Zeitschriftentitel:
J Immunol 
Jahr:
2010 
Band / Volume:
184 
Heft / Issue:
11 
Seitenangaben Beitrag:
6161-9 
Sprache:
eng 
Print-ISSN:
0022-1767 
TUM Einrichtung:
r Molekulare Allergologie und Umweltforschung