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Document type:
Zeitschriftenaufsatz 
Author(s):
Marczynski, Matthias; Käsdorf, Benjamin T.; Altaner, Bernhard; Wenzler, Andreas; Gerland, Ulrich; Lieleg, Oliver 
Title:
Transient binding promotes molecule penetration into mucin hydrogels by enhancing molecular partitioning 
Abstract:
Here, we present a microfluidics chip platform which allows for studying the charge-dependent transport of molecules across the interface of acidic mucin gels. With this setup, we demonstrate a selective accumulation of molecules at the liquid/gel interface of mucin hydrogels that occurs as a function of the molecule charge: this phenomenon is strongly pronounced for cationic molecules, weakly pronounced for anionic molecules and absent for neutral molecules. We suggest that molecular transport...    »
 
Dewey Decimal Classification:
570 Biowissenschaften, Biologie 
Journal title:
Biomaterials Science 
Year:
2018 
Journal volume:
Journal issue:
12 
Pages contribution:
3373-3387 
Covered by:
Scopus 
Reviewed:
ja 
Language:
en 
Fulltext / DOI:
Publisher:
Royal Society of Chemistry (RSC) 
E-ISSN:
2047-48302047-4849 
Date of publication:
01.01.2018 
TUM Institution:
Fachgebiet für Biomechanik, MW