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Document type:
journal article 
Author(s):
Dreher, Constantin; Oechsner, Markus; Mayinger, Michael; Beierl, Stefanie; Duma, Marciana-Nona; Combs, Stephanie E; Habermehl, Daniel 
Title:
Evaluation of the tumor movement and the reproducibility of two different immobilization setups for image-guided stereotactic body radiotherapy of liver tumors. 
Abstract:
The purpose of this study is to evaluate the tumor movement and accuracy of patient immobilization in stereotactic body radiotherapy of liver tumors with low pressure foil or abdominal compression.Fifty-four liver tumors treated with stereotactic body radiotherapy were included in this study. Forty patients were immobilized by a vacuum couch with low pressure foil, 14 patients by abdominal compression. We evaluated the ratio of gross tumor volume/internal target volume, the tumor movement in 4D-computed tomography scans and daily online adjustments after cone beam computed tomography scans.The ratio of gross tumor volume/internal target volume was smaller with low pressure foil. The tumor movement in 4D-computed tomography scans was smaller with abdominal compression, the cranial movement even significantly different (p = 0.02). The mean online adjustments and their mean absolute values in the vertical, lateral and longitudinal axis were smaller with abdominal compression. The online adjustments were significantly different (p< 0.013), their absolute values in case of the longitudinal axis (p = 0.043). There was no significant difference of the adjustments' 3D vectors.In comparison to low pressure foil, abdominal compression leads to a reduction of the tumor movement. Online adjustments decreased significantly, thus leading to higher accuracy in patient positioning. 
Journal title abbreviation:
Radiat Oncol 
Year:
2018 
Journal volume:
13 
Journal issue:
Pages contribution:
15 
Language:
eng 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie