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Dokumenttyp:
journal article 
Autor(en):
Schick, Markus; Habringer, Stefan; Nilsson, Jonas A; Keller, Ulrich 
Titel:
Pathogenesis and therapeutic targeting of aberrant MYC expression in haematological cancers. 
Abstract:
Identifying and therapeutically targeting cancer cell liabilities is of utmost importance in order to improve the treatment of patients with malignancies of poor prognosis. The MYC family genes (MYC, MYCN and MYCL) are among the most deregulated proto-oncogenes in human cancer. Aberrant MYC expression is frequently associated with poor prognosis. Although many aspects of MYC-mediated tumour biology are well characterized, there are currently no effective means for targeting MYC in a specific man...    »
 
Zeitschriftentitel:
Br J Haematol 
Jahr:
2017 
Band / Volume:
179 
Heft / Issue:
Seitenangaben Beitrag:
724-738 
Sprache:
eng 
Print-ISSN:
0007-1048 
TUM Einrichtung:
Klinik und Poliklinik für Innere Medizin III