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Document type:
journal article 
Author(s):
Al-Chalabi, Ahmed; Matevossian, Edouard; von Thaden, Anne; Schreiber, Catherine; Radermacher, Peter; Huber, Wolfgang; Perez Ruiz de Garibay, Aritz; Kreymann, Bernhard 
Title:
Evaluation of an ADVanced Organ Support (ADVOS) system in a two-hit porcine model of liver failure plus endotoxemia. 
Abstract:
Novel extracorporeal procedures are constantly being developed and evaluated for use in patients with sepsis. Preclinical evaluation of such procedures usually requires testing in large animal models. In the present work, the safety and efficacy of a recently developed ADVanced Organ Support (ADVOS) system in a newly developed large animal two-hit model of liver failure combined with endotoxemia were tested.After establishing the model in more than 50 animals, a randomized study was performed. A...    »
 
Journal title abbreviation:
Intensive Care Med Exp 
Year:
2017 
Journal volume:
Journal issue:
Pages contribution:
31 
Language:
eng 
Print-ISSN:
2197-425X 
TUM Institution:
Klinik und Poliklinik für Chirurgie