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Document type:
journal article 
Author(s):
Maertens, Yvonne; Humberg, Verena; Erlmeier, Franziska; Steffens, Sandra; Steinestel, Julie; Bögemann, Martin; Schrader, Andres Jan; Bernemann, Christof 
Title:
Comparison of isolation platforms for detection of circulating renal cell carcinoma cells. 
Abstract:
Analysis of circulating tumor cells (CTCs) has progressed in several tumor entities. However, little is known about CTCs in clear cell renal cell carcinoma (ccRCC) patients. Aim of our studies was to build a stable in vitro fundament for isolation of CTCs in ccRCC.We compared the analytical performance of different CTC isolation methods with regard to yield and purity: EpCAM based enrichment, leukocyte depletion and size based enrichment. EpCAM and cytokeratin 8 (KRT8) as biomarker for CTCs expr...    »
 
Journal title abbreviation:
Oncotarget 
Year:
2017 
Journal volume:
Journal issue:
50 
Pages contribution:
87710-87717 
Language:
eng 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie