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Dokumenttyp:
journal article 
Autor(en):
Ettl, Johannes; Klein, Evelyn; Hapfelmeier, Alexander; Grosse Lackmann, Kirsten; Paepke, Stefan; Petry, Christoph; Specht, Katja; Wolff, Laura; Höfler, Heinz; Kiechle, Marion 
Titel:
Decision impact and feasibility of different ASCO-recommended biomarkers in early breast cancer: Prospective comparison of molecular marker EndoPredict and protein marker uPA/PAI-1. 
Abstract:
Adjuvant therapy decisions in early breast cancer are based on accurate risk assessment. Urokinase plasminogen activator (uPA) and plaminogen activator inhibitor-1 (PAI-1) have been the first biomarkers in hormone receptor (HR) positive breast cancer to reach highest level of evidence. The EndoPredict test (EPclin) combines gene expression information with nodal status and tumor size. The aim of this prospective study was to compare uPA/PAI-1 and EPclin as prognostic biomarkers with regard to fe...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2017 
Band / Volume:
12 
Heft / Issue:
Seitenangaben Beitrag:
e0183917 
Sprache:
eng 
TUM Einrichtung:
Institut für Medizinische Informatik, Statistik und Epidemiologie; Klinik und Poliklinik für Frauenheilkunde; Institut für Allgemeine Pathologie und pathologische Anatomie