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Document type:
journal article 
Author(s):
Tzoumas, Stratis; Kravtsiv, Andrii; Gao, Yuan; Buehler, Andreas; Ntziachristos, Vasilis 
Title:
Statistical Molecular Target Detection Framework for Multispectral Optoacoustic Tomography. 
Abstract:
Statistical sub-pixel detection via the adaptive matched filter (AMF) has been shown to improve the molecular imaging sensitivity and specificity of optoacoustic (photoacoustic) imaging. Applied to multispectral optoacoustic tomography (MSOT), AMF assumes that the spatially-varying tissue spectra follow a multivariate Gaussian distribution, that the spectrum of the target molecule is precisely known and that the molecular target lies in "low probability" within the data. However, when these assu...    »
 
Journal title abbreviation:
IEEE Trans Med Imaging 
Year:
2016 
Journal volume:
35 
Journal issue:
12 
Pages contribution:
2534-2545 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0278-0062 
TUM Institution:
Lehrstuhl für Biologische Bildgebung