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Dokumenttyp:
journal article 
Autor(en):
Hessmann, E; Schneider, G; Ellenrieder, V; Siveke, J T 
Titel:
MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies. 
Abstract:
Owing to its aggressiveness, late detection and marginal therapeutic accessibility, pancreatic ductal adenocarcinoma (PDAC) remains a most challenging malignant disease. Despite scientific progress in the understanding of the mechanisms that underly PDAC initiation and progression, the successful translation of experimental findings into effective new therapeutic strategies remains a largely unmet need. The oncogene MYC is activated in many PDAC cases and is a master regulator of vital cellular...    »
 
Zeitschriftentitel:
Oncogene 
Jahr:
2016 
Band / Volume:
35 
Heft / Issue:
13 
Seitenangaben Beitrag:
1609-18 
Sprache:
eng 
Print-ISSN:
0950-9232 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik