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Document type:
journal article 
Author(s):
Zvereva, Alexandra; Petoussi-Henss, Nina; Li, Wei Bo; Schlattl, Helmut; Oeh, Uwe; Zankl, Maria; Graner, Frank Philipp; Hoeschen, Christoph; Nekolla, Stephan G; Parodi, Katia; Schwaiger, Markus 
Title:
Effect of blood activity on dosimetric calculations for radiopharmaceuticals. 
Abstract:
The objective of this work was to investigate the influence of the definition of blood as a distinct source on organ doses, associated with the administration of a novel radiopharmaceutical for positron emission tomography-computed tomography (PET/CT) imaging-(S)-4-(3-(18)F-fluoropropyl)-L-glutamic acid ((18)F-FSPG). Personalised pharmacokinetic models were constructed based on clinical PET/CT images from five healthy volunteers and blood samples from four of them. Following an identifiability a...    »
 
Journal title abbreviation:
Phys Med Biol 
Year:
2016 
Journal volume:
61 
Journal issue:
21 
Pages contribution:
7688-7703 
Language:
eng 
Print-ISSN:
0031-9155 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik