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Document type:
journal article 
Author(s):
Prokopchuk, Olga; Steinacker, Jürgen M; Nitsche, Ulrich; Otto, Stephanie; Bachmann, Jeannine; Schubert, Elaine C; Friess, Helmut; Martignoni, Marc E 
Title:
IL-4 mRNA Is Downregulated in the Liver of Pancreatic Cancer Patients Suffering from Cachexia. 
Abstract:
Interleukin-4 (IL-4) together with interleukin-13 (IL-13) play an important role in inflammation and wound repair, and are known to be upregulated in human skeletal muscle after strenuous physical exercise. Additionally, these cytokines may act as autocrine growth factors in pancreatic cancer cells. We hypothesize that IL-4, IL-13, and their corresponding receptors are involved in mechanism of cancer cachexia.Tissue samples from human skeletal muscle, white fat, liver, healthy pancreas, and panc...    »
 
Journal title abbreviation:
Nutr Cancer 
Year:
2017 
Journal volume:
69 
Journal issue:
Pages contribution:
84-91 
Language:
eng 
Print-ISSN:
0163-5581 
TUM Institution:
Chirurgiesche Klinik und Poliklinik; Institut für Radiologie