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Document type:
journal article 
Author(s):
Müller, Anne; Kleinau, Gunnar; Piechowski, Carolin L; Müller, Timo D; Finan, Brian; Pratzka, Juliane; Grüters, Annette; Krude, Heiko; Tschöp, Matthias; Biebermann, Heike 
Title:
G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity. 
Abstract:
The G-protein coupled receptor 83 (GPR83) is an orphan G-protein coupled receptor for which the natural ligand(s) and signaling pathway(s) remain to be identified. Previous studies suggest a role of GPR83 in the regulation of thermogenesis and the control of circulating adiponectin. The aim of this study was to gain insights into the molecular underpinnings underlying GPR83 signaling. In particular, we aimed to assess the underlying G-protein activated signaling pathway of GPR83 and how this pat...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2013 
Journal volume:
Journal issue:
Pages contribution:
e53347 
Language:
eng 
TUM Institution:
Fakultät für Medizin (zentral angehängte Professuren und Einrichtungen: Profs. Tschöp, Berberat; TUMCells, ZPF, MSZ)