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Dokumenttyp:
journal article 
Autor(en):
Müller, Anne; Kleinau, Gunnar; Piechowski, Carolin L; Müller, Timo D; Finan, Brian; Pratzka, Juliane; Grüters, Annette; Krude, Heiko; Tschöp, Matthias; Biebermann, Heike 
Titel:
G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity. 
Abstract:
The G-protein coupled receptor 83 (GPR83) is an orphan G-protein coupled receptor for which the natural ligand(s) and signaling pathway(s) remain to be identified. Previous studies suggest a role of GPR83 in the regulation of thermogenesis and the control of circulating adiponectin. The aim of this study was to gain insights into the molecular underpinnings underlying GPR83 signaling. In particular, we aimed to assess the underlying G-protein activated signaling pathway of GPR83 and how this pat...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2013 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e53347 
Sprache:
eng 
TUM Einrichtung:
Fakultät für Medizin (zentral angehängte Professuren und Einrichtungen: Profs. Tschöp, Berberat; TUMCells, ZPF, MSZ)