User: Guest  Login
Document type:
Zeitschriftenaufsatz 
Author(s):
Lohr, Kerstin; Pachl, Fiona; Moghaddas Gholami, Amin; Geillinger, Kerstin E.; Daniel, Hannelore; Kuster, Bernhard; Klingenspor, Martin 
Title:
Reduced mitochondrial mass and function add to age‐related susceptibility toward diet‐induced fatty liver in C57BL/6J mice 
Abstract:
Nonalcoholic fatty liver disease (NAFLD) is a major health burden in the aging society with an urging medical need for a better understanding of the underlying mechanisms. Mitochondrial fatty acid oxidation and mitochondrial-derived reactive oxygen species (ROS) are considered critical in the development of hepatic steatosis, the hallmark of NAFLD. Our study addressed in C57BL/6J mice the effect of high fat diet feeding and age on liver mitochondria at an early stage of NAFLD development. We the...    »
 
Keywords:
BayBioMS 
Journal title:
Physiological Reports 
Year:
2016 
Journal volume:
Journal issue:
19 
Pages contribution:
e12988 
Fulltext / DOI:
Publisher:
Wiley-Blackwell 
E-ISSN:
2051-817X2051-817X 
Date of publication:
29.09.2016