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Document type:
journal article 
Author(s):
Razansky, Daniel, D; Harlaar, Niels J, NJ; Hillebrands, Jan Luuk, JL; Taruttis, Adrian, A; Herzog, Eva, E; Zeebregts, Clark J, CJ; van Dam, Gooitzen M, GM; Ntziachristos, Vasilis, V 
Title:
Multispectral optoacoustic tomography of matrix metalloproteinase activity in vulnerable human carotid plaques. 
Abstract:
Elevated expression of cathepsins, integrins and matrix metalloproteinases (MMPs) is typically associated with atherosclerotic plaque instability. While fluorescent tagging of such molecules has been amply demonstrated, no imaging method was so far shown capable of resolving these inflammation-associated tags with high fidelity and resolution beyond microscopic depths. This study is aimed at demonstrating a new method with high potential for noninvasive clinical cardiovascular diagnostics of vul...    »
 
Journal title abbreviation:
Mol Imaging Biol 
Year:
2012 
Journal volume:
14 
Journal issue:
Pages contribution:
277-85 
Language:
eng 
Print-ISSN:
1536-1632 
TUM Institution:
Lehrstuhl für Biologische Bildgebung