Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Yang, J; Loos, RJ; Powell, JE; Medland, SE; Speliotes, EK; Chasman, DI; Rose, LM; Thorleifsson, G; Steinthorsdottir, V; Mägi, R; Waite, L; Smith, AV; Yerges-Armstrong, LM; Monda, KL; Hadley, D; Mahajan, A; Li, G; Kapur, K; Vitart, V; Huffman, JE; Wang, SR; Palmer, C; Esko, T; Fischer, K; Zhao, JH; Demirkan, A; Isaacs, A; Feitosa, MF; Luan, J; Heard-Costa, NL; White, C; Jackson, AU; Preuss, M; Ziegler, A; Eriksson, J; Kutalik, Z; Frau, F; Nolte, IM; Van Vliet-Ostaptchouk, JV; Hottenga, JJ; Jacobs...    »
 
Titel:
FTO genotype is associated with phenotypic variability of body mass index. 
Abstract:
There is evidence across several species for genetic control of phenotypic variation of complex traits, such that the variance among phenotypes is genotype dependent. Understanding genetic control of variability is important in evolutionary biology, agricultural selection programmes and human medicine, yet for complex traits, no individual genetic variants associated with variance, as opposed to the mean, have been identified. Here we perform a meta-analysis of genome-wide association studies of...    »
 
Zeitschriftentitel:
Nature 
Jahr:
2012 
Band / Volume:
490 
Heft / Issue:
7419 
Seitenangaben Beitrag:
267-72 
Sprache:
eng 
Print-ISSN:
0028-0836 
TUM Einrichtung:
r Herz- und Kreislauferkrankungen