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Dokumenttyp:
journal article 
Autor(en):
Paris, PL; Hofer, MD; Albo, G; Kuefer, R; Gschwend, JE; Hautmann, RE; Fridyland, J; Simko, J; Carroll, PR; Rubin, MA; Collins, C 
Titel:
Genomic profiling of hormone-naïve lymph node metastases in patients with prostate cancer. 
Abstract:
The progression of organ-confined prostate cancer to metastatic cancer is inevitably fatal. Consequently, identification of structural changes in the genome and associated transcriptional responses that drive this progression is critical to understanding the disease process and the development of biomarkers and therapeutic targets. In this study, whole genome copy number changes in genomes of hormone-naïve lymph node metastases were profiled using array comparative genomic hybridization, and mat...    »
 
Zeitschriftentitel:
Neoplasia 
Jahr:
2006 
Band / Volume:
Heft / Issue:
12 
Seitenangaben Beitrag:
1083-9 
Sprache:
eng 
Print-ISSN:
1522-8002 
TUM Einrichtung:
Urologische Klinik und Poliklinik