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Dokumenttyp:
journal article 
Autor(en):
Fu, Y; Nitecki, DE; Maltby, D; Simon, GH; Berejnoi, K; Raatschen, HJ; Yeh, BM; Shames, DM; Brasch, RC 
Titel:
Dendritic iodinated contrast agents with PEG-cores for CT imaging: synthesis and preliminary characterization. 
Abstract:
The purpose of this study was to design, synthesize, and initially characterize a representative set of novel constructs for large-molecular radiographic/computed tomography (CT) contrast agents, intended for a primarily intravascular distribution. A new assembly of well-known and biocompatible components consists of paired, symmetrical dendritic polylysines initiated from both ends of a poly(ethylene glycol) (PEG) core, yielding an array of multiple free amino groups to which were conjugated hi...    »
 
Zeitschriftentitel:
Bioconjug Chem 
Jahr:
2006 
Band / Volume:
17 
Heft / Issue:
Seitenangaben Beitrag:
1043-56 
Sprache:
eng 
Print-ISSN:
1043-1802 
TUM Einrichtung:
r Radiologie