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Document type:
journal article 
Author(s):
Lu, L; Neff, F; Fischer, DA; Henze, C; Hirsch, EC; Oertel, WH; Schlegel, J; Hartmann, A 
Title:
Regional vulnerability of mesencephalic dopaminergic neurons prone to degenerate in Parkinson's disease: a post-mortem study in human control subjects. 
Abstract:
Parkinson's disease (PD) is characterized by loss of dopaminergic (DA) neurons in the human midbrain, which varies greatly among mesencephalic subregions. The genetic expression profiles of mesencephalic DA neurons particularly prone to degenerate during PD (nigrosome 1 within the substantia nigra pars compacta-SNpc) and those particularly resistant in the disease course (central grey substance-CGS) were compared in five control subjects by immuno-laser capture microdissection followed by RNA ar...    »
 
Journal title abbreviation:
Neurobiol Dis 
Year:
2006 
Journal volume:
23 
Journal issue:
Pages contribution:
409-21 
Language:
eng 
Print-ISSN:
0969-9961 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie