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Dokumenttyp:
journal article 
Autor(en):
Sikorski, K; Chmielewski, S; Przybyl, L; Heemann, U; Wesoly, J; Baumann, M; Bluyssen, HA 
Titel:
STAT1-mediated signal integration between IFN? and LPS leads to increased EC and SMC activation and monocyte adhesion. 
Abstract:
Inflammation plays an important role in host defenses against infectious agents and injury, but it also contributes to the pathophysiology of atherosclerosis. Signal transducer and activated transcription 1 (STAT1) has been identified as a point of convergence for the cross talk between the pro-inflammatory cytokine interferon ? (IFN?) and the Toll-like receptor-4 (TLR4) ligand LPS in immune cells. However, there is no information available on the role of STAT1 in TLR4-mediated progression of at...    »
 
Zeitschriftentitel:
Am J Physiol Cell Physiol 
Jahr:
2011 
Band / Volume:
300 
Heft / Issue:
Seitenangaben Beitrag:
C1337-44 
Sprache:
eng 
Print-ISSN:
0363-6143 
TUM Einrichtung:
r Nephrologie