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Dokumenttyp:
journal article 
Autor(en):
Wagner, H; Bauer, S 
Titel:
All is not Toll: new pathways in DNA recognition. 
Abstract:
Immunological defense depends on the ability of the innate immune system to recognize invading microbes as foreign and thus eliminate them. The Toll-like receptors (TLRs) help detect foreign invaders by sensing various pathogen-associated molecules, including microbial RNA and DNA. At present, it is unclear whether and how the immune system distinguishes between microbial and self nucleic acids, as host-derived RNA and DNA also stimulate TLRs. In addition, recent studies have revealed the existe...    »
 
Zeitschriftentitel:
J Exp Med 
Jahr:
2006 
Band / Volume:
203 
Heft / Issue:
Seitenangaben Beitrag:
265-8 
Sprache:
eng 
Print-ISSN:
0022-1007 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene