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Document type:
journal article 
Author(s):
Kalis, C; Gumenscheimer, M; Freudenberg, N; Tchaptchet, S; Fejer, G; Heit, A; Akira, S; Galanos, C; Freudenberg, MA 
Title:
Requirement for TLR9 in the immunomodulatory activity of Propionibacterium acnes. 
Abstract:
Propionibacterium acnes (formerly Corynebacterium parvum) is part of the human flora and, as such, is associated with several human pathologies. It possesses strong immunomodulatory activities, which makes this bacterium interesting for prophylactic and therapeutic vaccination. The bacterial component(s) and the host receptor(s) involved in the induction of these activities are poorly understood. We show in this study that TLR9 is crucial in generating the characteristic effects of killed P. acn...    »
 
Journal title abbreviation:
J Immunol 
Year:
2005 
Journal volume:
174 
Journal issue:
Pages contribution:
4295-300 
Language:
eng 
Print-ISSN:
0022-1767 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene