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Dokumenttyp:
journal article 
Autor(en):
Hallatschek, W; Fiedler, G; Kirschning, CJ; Creutzburg, F; Lamping, N; Nüssler, A; Schumann, RR 
Titel:
Inhibition of hepatic transcriptional induction of lipopolysaccharide-binding protein by transforming-growth-factor beta 1. 
Abstract:
LPS-binding protein (LBP) is an acute-phase protein with the ability to bind and transfer LPS of Gram-negative bacteria, as well as cell wall compounds of other pathogenic bacteria. This soluble pattern-recognition molecule is present in high concentrations in serum and represents an important defense mechanism of the host. Regulation of the hepatic acute-phase response and its termination are important mechanisms for limiting systemic inflammatory activity of the host organism. We show here tha...    »
 
Zeitschriftentitel:
Eur J Immunol 
Jahr:
2004 
Band / Volume:
34 
Heft / Issue:
Seitenangaben Beitrag:
1441-50 
Sprache:
eng 
Print-ISSN:
0014-2980 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene