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Dokumenttyp:
journal article 
Autor(en):
Lembo, A; Kalis, C; Kirschning, CJ; Mitolo, V; Jirillo, E; Wagner, H; Galanos, C; Freudenberg, MA 
Titel:
Differential contribution of Toll-like receptors 4 and 2 to the cytokine response to Salmonella enterica serovar Typhimurium and Staphylococcus aureus in mice. 
Abstract:
The contribution of murine Toll-like receptors 2 and 4 (TLR2 and -4, respectively) to cytokine induction by heat-killed bacteria was analyzed in vitro and in vivo. Gram-negative bacteria induced cytokines primarily via TLR4; the contribution of TLR2 was only minor. Neither TLR4 nor, surprisingly, TLR2 was required in the MyD88-dependent response to Staphylococcus aureus. 
Zeitschriftentitel:
Infect Immun 
Jahr:
2003 
Band / Volume:
71 
Heft / Issue:
10 
Seitenangaben Beitrag:
6058-62 
Sprache:
eng 
Print-ISSN:
0019-9567 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene