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Dokumenttyp:
journal article 
Autor(en):
Prebeck, S; Brade, H; Kirschning, CJ; da Costa, CP; Dürr, S; Wagner, H; Miethke, T 
Titel:
The Gram-negative bacterium Chlamydia trachomatis L2 stimulates tumor necrosis factor secretion by innate immune cells independently of its endotoxin. 
Abstract:
The endotoxin of Chlamydia trachomatis L(2), the causative agent of lymphogranuloma venerum, has been described as an endotoxin with an atypical structure and weak stimulatory activity. It is, however, unclear whether chlamydial endotoxin plays a role in the stimulation of innate immune cells upon contact with the whole microorganism C. trachomatis L(2). We show here that chlamydial endotoxin and, as expected, Escherichia coli O55:B5 endotoxin depend on Toll-like receptor 4 without depending on...    »
 
Zeitschriftentitel:
Microbes Infect 
Jahr:
2003 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
463-70 
Sprache:
eng 
Print-ISSN:
1286-4579 
TUM Einrichtung:
r Virologie; r Medizinische Mikrobiologie, Immunologie und Hygiene