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Dokumenttyp:
journal article 
Autor(en):
Liebig, B; Brabletz, T; Staege, MS; Wulfänger, J; Riemann, D; Burdach, S; Ballhausen, WG 
Titel:
Forced expression of deltaN-TCF-1B in colon cancer derived cell lines is accompanied by the induction of CEACAM5/6 and mesothelin. 
Abstract:
The colon cancer cell lines HT29 and SW480 were transfected with an N-terminal beta-catenin binding site-deficient high mobility group (HMG)-box T-cell factor 1 (deltaN-TCF-1) construct to identify differentially expressed genes. Oligonucleotide HG-U133A microarray expression profiling revealed increased mRNA levels of carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 5, 6 and mesothelin in transfectants positive for nuclear deltaN-TCF-1B. Increased amounts of CEACAM5 (CEA) were d...    »
 
Zeitschriftentitel:
Cancer Lett 
Jahr:
2005 
Band / Volume:
223 
Heft / Issue:
Seitenangaben Beitrag:
159-67 
Sprache:
eng 
Print-ISSN:
0304-3835 
TUM Einrichtung:
Kinderklinik und Poliklinik