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Document type:
journal article 
Author(s):
Hofmann, HS; Hansen, G; Richter, G; Taege, C; Simm, A; Silber, RE; Burdach, S 
Title:
Matrix metalloproteinase-12 expression correlates with local recurrence and metastatic disease in non-small cell lung cancer patients. 
Abstract:
PURPOSE: Non-small cell lung cancer (NSCLC) is a very common and aggressive malignancy. Survival after resection of tumor is especially determined by the occurrence of distant metastasis. Matrix metalloproteinases (MMP) support this metastatic process by degradation of the extracellular matrix. EXPERIMENTAL DESIGN: We used DNA microarray technology to examine the expression of 22 MMPs in 89 surgically treated NSCLC patients. Validation of microarray results was done using reverse transcription-P...    »
 
Journal title abbreviation:
Clin Cancer Res 
Year:
2005 
Journal volume:
11 
Journal issue:
Pages contribution:
1086-92 
Language:
eng 
Print-ISSN:
1078-0432 
TUM Institution:
Kinderklinik und Poliklinik