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Document type:
journal article 
Author(s):
Achenbach, P; Warncke, K; Reiter, J; Naserke, HE; Williams, AJ; Bingley, PJ; Bonifacio, E; Ziegler, AG 
Title:
Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics. 
Abstract:
Family history of type 1 diabetes and autoantibodies to the islet antigens insulin (IAA), glutamate decarboxylase (GADA), and the protein tyrosine phosphatase-like protein IA-2 (IA-2A) are strong predictors of type 1 diabetes, but the rate of progression to diabetes in multiple islet autoantibody-positive relatives varies widely. We asked whether detailed characterization of islet autoantibodies that included determination of titer, epitope specificity, and IgG subclass would improve diabetes pr...    »
 
Journal title abbreviation:
Diabetes 
Year:
2004 
Journal volume:
53 
Journal issue:
Pages contribution:
384-92 
Language:
eng 
Print-ISSN:
0012-1797 
TUM Institution:
Kinderklinik und Poliklinik