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Dokumenttyp:
journal article 
Autor(en):
Wagenpfeil, S; Treiber, U; Lehmer, A 
Titel:
Statistical analysis of combined dose effects for experiments with two agents. 
Abstract:
OBJECTIVE: Classical isobologram analysis offers a way for analysing combined drug effects in dose-response experiments statistically. The aim is to determine as to whether two agents or drugs can be considered synergistic or antagonistic in their effect. METHODS AND MATERIALS: We describe a MATLAB-based software tool for automated isobologram analysis and computation of combination indices. Statistical issues like estimation together with respective confidence intervals are of key interest. Add...    »
 
Zeitschriftentitel:
Artif Intell Med 
Jahr:
2006 
Band / Volume:
37 
Heft / Issue:
Seitenangaben Beitrag:
65-71 
Sprache:
eng 
Print-ISSN:
0933-3657 
TUM Einrichtung:
r Medizinische Statistik und Epidemiologie; Urologische Klinik und Poliklinik