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Dokumenttyp:
journal article 
Autor(en):
Laws, SM; Perneczky, R; Wagenpfeil, S; Müller, U; Förstl, H; Martins, RN; Kurz, A; Riemenschneider, M 
Titel:
TNF polymorphisms in Alzheimer disease and functional implications on CSF beta-amyloid levels. 
Abstract:
Alzheimer disease (AD), vascular dementia, and stroke are all associated with inflammation though their respective initiating factors differ. Recently a polymorphism in the proinflammatory cytokine tumor necrosis factor (TNF), in association with apolipoprotein E (APOE), was reported to increase AD risk. Two SNPs, rs1799724 (-850C>T; NT_007592.14:g.22400733C>T) and rs1800629 (-308G>A; [NT_007592.14:g.22401282G>A]), and the APOE polymorphism were genotyped in 506 patients with sporadic AD and i...    »
 
Zeitschriftentitel:
Hum Mutat 
Jahr:
2005 
Band / Volume:
26 
Heft / Issue:
Seitenangaben Beitrag:
29-35 
Sprache:
eng 
Print-ISSN:
1059-7794 
TUM Einrichtung:
r Psychiatrie und Psychotherapie; r Medizinische Statistik und Epidemiologie