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Dokumenttyp:
journal article 
Autor(en):
Grzywacz, B; Kataria, N; Sikora, M; Oostendorp, RA; Dzierzak, EA; Blazar, BR; Miller, JS; Verneris, MR 
Titel:
Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells. 
Abstract:
The stages of human natural killer (NK) cell differentiation are not well established. Culturing CD34(+) progenitors with interleukin 7 (IL-7), IL-15, stem cell factor (SCF), FLT-3L, and murine fetal liver cell line (EL08.1D2), we identified 2 nonoverlapping subsets of differentiating CD56(+) cells based on CD117 and CD94 (CD117(high)CD94(-) and CD117(low/-)CD94(+) cells). Both populations expressed CD161 and NKp44, but differed with respect to NKp30, NKp46, NKG2A, NKG2C, NKG2D, CD8, CD16, and K...    »
 
Zeitschriftentitel:
Blood 
Jahr:
2006 
Band / Volume:
108 
Heft / Issue:
12 
Seitenangaben Beitrag:
3824-33 
Sprache:
eng 
Print-ISSN:
0006-4971 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik