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Dokumenttyp:
Journal Article; Article
Autor(en):
Bassermann, F; Peschel, C; Duyster, J
Titel:
Mitotic entry: a matter of oscillating destruction.
Abstract:
Entry into mitosis is essentially driven by cyclin B1 and its associated catalytically active partner Cdk1. While cyclin B1 is kept cytoplasmic throughout interphase, nuclear accumulation occurs just prior to mitosis. This restriction is thought to be part of an oscillating mechanism to properly time mitotic entry. A novel nuclear SCF-type mammalian E3 ligase defined by the F-box containing protein NIPA (nuclear interaction partner of ALK), SCFNIPA, targets nuclear cyclin B1 in interphase while...     »
Zeitschriftentitel:
Cell Cycle
Jahr:
2005
Band / Volume:
4
Heft / Issue:
11
Seitenangaben Beitrag:
1515-7
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16258267
Print-ISSN:
1538-4101
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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